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Intravenous Vs. Intraosseous Vascular Access During Out-of-Hospital
Sponsor: Lars Wiuff Andersen
Summary
The "Intravenous vs. Intraosseous Vascular Access During Out-of-Hospital Cardiac Arrest (IVIO)"-trial is an investigator-initiated, randomized, parallel group, patient and outcome assessor-blinded, superiority trial of intravenous vs. intraosseous vascular access during adult out-of-hospital cardiac arrest. The intraosseous group will be further randomized to humeral vs. tibial access. The trial will be conducted in the Central Denmark Region. The primary outcome will be sustained return of spontaneous circulation, and 762 patients will be included. Key secondary outcomes include survival at 30 days and survival at 30 days with a favorable neurological outcome.
Official title: Intravenous Vs. Intraosseous Vascular Access During Out-of-Hospital Cardiac Arrest - a Randomized Clinical Trial
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
1479
Start Date
2022-03-01
Completion Date
2025-05-05
Last Updated
2024-09-19
Healthy Volunteers
No
Conditions
Interventions
Intraosseous access
Needle placed in the bone marrow.
Intravenous
Needle placed in a vein.
Locations (5)
Emergency Medical Services, the North Denmark Region
Aalborg, Denmark
Prehospital Emergency Medical Services, Central Denmark Region
Aarhus N, Denmark
Copenhagen Emergency Medical Services, the Capital Region of Denmark
Ballerup Municipality, Denmark
The Prehospital Center, Region Zealand
Næstved, Denmark
Emergency Medical Services, the Region of Southern Denmark
Vejle, Denmark