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ACTIVE NOT RECRUITING
NCT05205031
PHASE4

Intravenous Vs. Intraosseous Vascular Access During Out-of-Hospital

Sponsor: Lars Wiuff Andersen

View on ClinicalTrials.gov

Summary

The "Intravenous vs. Intraosseous Vascular Access During Out-of-Hospital Cardiac Arrest (IVIO)"-trial is an investigator-initiated, randomized, parallel group, patient and outcome assessor-blinded, superiority trial of intravenous vs. intraosseous vascular access during adult out-of-hospital cardiac arrest. The intraosseous group will be further randomized to humeral vs. tibial access. The trial will be conducted in the Central Denmark Region. The primary outcome will be sustained return of spontaneous circulation, and 762 patients will be included. Key secondary outcomes include survival at 30 days and survival at 30 days with a favorable neurological outcome.

Official title: Intravenous Vs. Intraosseous Vascular Access During Out-of-Hospital Cardiac Arrest - a Randomized Clinical Trial

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

1479

Start Date

2022-03-01

Completion Date

2025-05-05

Last Updated

2024-09-19

Healthy Volunteers

No

Conditions

Interventions

DEVICE

Intraosseous access

Needle placed in the bone marrow.

DEVICE

Intravenous

Needle placed in a vein.

Locations (5)

Emergency Medical Services, the North Denmark Region

Aalborg, Denmark

Prehospital Emergency Medical Services, Central Denmark Region

Aarhus N, Denmark

Copenhagen Emergency Medical Services, the Capital Region of Denmark

Ballerup Municipality, Denmark

The Prehospital Center, Region Zealand

Næstved, Denmark

Emergency Medical Services, the Region of Southern Denmark

Vejle, Denmark