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RECRUITING
NCT05206500
PHASE4

NextGen - Clinical Implication of Next Generation Sequencing

Sponsor: Wake Forest University Health Sciences

View on ClinicalTrials.gov

Summary

Recently more advanced techniques, including Polymerase Chain Reaction (PCR) and Next Generation Sequencing (NGS) are available to detect bacteria in urine based on bacterial genomes. Comparing to traditional culture, these techniques have more sensitivity and could potentially be of a great help in patients with Colony Count of less than 10,000 and more than zero.

Official title: Clinical Implication of Next Generation Sequencing of Urinary Bacteria in Patients With Low Colony Forming Units of Bacteria in Traditional Urine Culture

Key Details

Gender

FEMALE

Age Range

18 Years - 80 Years

Study Type

INTERVENTIONAL

Enrollment

100

Start Date

2022-05-17

Completion Date

2028-12

Last Updated

2025-12-08

Healthy Volunteers

No

Interventions

DRUG

Antibiotic

FDA approved and marketed antibiotic treatment for the patients with UTI symptoms and CC \>0 and \<10,000

DEVICE

Next Gen

Next Generation Sequencing (NGS) is available to detect bacteria in urine based on bacterial genomes.

Locations (1)

Wake Forest Health Sciences

Winston-Salem, North Carolina, United States