Clinical Research Directory
Browse clinical research sites, groups, and studies.
Mapping the Human Appendix Using Single Cell Sequencing
Sponsor: Bispebjerg Hospital
Summary
The overall purpose of this study is to describe the cellular composition of the human appendix and its gene expression using scRNAseq and scATACseq methods. This will potentially provide is with a complete and detailed map of the appendix´ immunological properties and its role in neuro-endocrine/metabolic functions. Our results will be held up against current knowledge of the appendix and its role in the human body and thus hopefully expand our understanding of this organ and the consequences of its removal by appendectomy.
Official title: Cellular Composition of the Human Appendix Using Single-cell RNA and Single-cell ATAC-sequencing.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
5
Start Date
2023-02-01
Completion Date
2026-06-10
Last Updated
2026-06-12
Healthy Volunteers
No
Interventions
Biopsy
Participants included in the study, will have a full thickness biopsy of the middle of the appendix taken, after the resected bowel has been removed during surgery.
Locations (1)
Bispebjerg University Hospital
Copenhagen, Denmark