Clinical Research Directory

Inclusion Criteria: 1. patient who have pathologic confirmation of Ductal carcinoma in situ or invasive caricinoma 2. patient who undergone nipple sparing mastectomy with construction 3. patient who considered radiotherapy in breast cancer at stage IIB or lower (exclude ≥T3, ≥N2) 4. patient who have not distant metastasis 5. age \>19 years old 6. patinet who have an ECOG of 0-2 7. patient who have not comorbidities(collagne vascular disease, such as systemic lupus erythermatosis, scleroderma, dermatomyositis) 8. patient who have not prior radiotherapy history in treatment site 9. patient who have not pregnancy or lacting 10. patient who have consent in writing to participate in research Exclusion Criteria: 1. patient who undergone construction after nipple sparing mastectomy 2. patient who have ≥T3, ≥N2 in breast cancer 3. patient who have diastant metastasis 4. patient who have comorbidities(collagne vascular disease, such as systemic lupus erythermatosis, scleroderma, dermatomyositis) 5. patient who have treatment history in treatment site 6. patinet who have an ECOG 3-4 7. age \< 20years old 8. patient who have pregnancy or lacting 9. patient who have not consent in writing to participate in research