Clinical Research Directory

Inclusion Criteria: * Adult patient * Effective contraception for the duration of research for fertile women of childbearing age * Unilateral Rutherford 2 or 3 symptomatic Lower Extremity Artery Disease (LEAD) arteritic patient with a lesion of the superficial femoral artery Trans-Atlantic Inter-Society Consensus (TASC) C or D between 15 and 25 cm * Patient eligible for bypass surgery and endovascular procedure * No alteration of the upstream flow (iliac flow preserved or restored) * Patient with at least one patent artery below the knee * Patient informed and having signed the information and consent form to participate in the study Exclusion Criteria: * Known pregnancy or breastfeeding * Iliac flow altered upstream * History of surgery or stent on the affected superficial femoral artery * Concomitant bacteremia (positive blood cultures in the 7 days preceding the procedure) * Known intolerance to antiaggregants or heparin * Contraindication to the endovascular procedure (severe renal failure contraindicating the injection of contrast product despite prior hydration, known severe allergy to iodinated contrast product \[unless the center chooses to use carbon dioxide injection\]) or bypass surgery (cardiovascular, respiratory or other comorbidities, contraindicating general anesthesia, local contraindications for bypass: skin lesion at the operative site) * No affiliation to a social security regime or to another social protection regime * Patient deprived of liberty or under legal protection (guardianship, trusteeship) * Inability, according to the investigator, to understand or refusal to sign the informed consent to participate in the study (non-French speaking patient, cognitive disorders) * Ongoing participation in another research protocol Participation in non-interventional research is authorized Secondary exclusion criterion: * Negative opinion from the anesthesiologist-resuscitator at the end of the pre-anesthetic consultation * Positive pregnancy test from the pre-operative laboratory test (result received after obtaining consent, but before the surgical procedure)