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Coronary Computed Tomography Angiography For Optimized Invasive Coronary examInation
Sponsor: Aarhus University Hospital Skejby
Summary
Coronary computed tomography angiography (CCTA) is a non-invasive method for visualization of the coronary arteries. The anatomical information obtained by CCTA, however, is rarely integrated into a subsequent coronary intervention. The CT-FOCI trial aims to evaluate, in a randomized setting, the benefit of implementing the information obtained by CCTA as part of the invasive examination using a CT-guided algorithm (CTGA). Patients (n=120) with symptoms of stable angina pectoris will be randomized 1:1 after CCTA has determined at least 1 stenosis with luminal diameter reduction of minimum 50% in a vessel segment \> 2 mm in diameter. Subsequent, invasive examination and intervention will utilize the information available according to randomization. Primary efficacy endpoints are a reduction in patient radiation exposure, procedure time, procedural utensils, and contrast use. Secondary endpoints is significant stenosis in the non-target vessel, only available in the conventional group.
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
122
Start Date
2022-05-01
Completion Date
2025-02-28
Last Updated
2026-08-26
Healthy Volunteers
No
Interventions
CCTA guided focused coronary angiography examination.
Focused examination based on Images from CCTA, by choice of optimal catheter used and projection.
Locations (1)
Aarhus University Hospital, Depart. of Cardiology
Aarhus N, Central Region, Denmark