Clinical Research Directory

Inclusion Criteria: 1. Invasive mechanical ventilation for more than 48 hours 2. Patients indicated, according to intensivists, for carrying out a spontaneous breathing trial weaning test, based on the presence of all of the following criteria: 1. SpO2\> 90% with FiO2 ≤40% and PEEP ≤5 cmH2O 2. Cough effectiveness on tracheal aspirations 3. Lack of hemodynamic instability and of disorders of consciousness 3. Patients at high risk of weaning-induced pulmonary edema (WIPO), defined by one or more of the following criteria: 1. Obesity, defined by a body mass index\> 30 kg/m² 2. Chronic obstructive pulmonary disease 3. Chronic heart disease Exclusion Criteria: 1. Age \<18 years and pregnant women 2. Patients with a decision of not to resuscitate 3. Poor echogenicity 4. Severe mitral valve disease (leakage and/or stenosis, bioprosthesis) 5. Patients with pacemaker 6. Tracheostomy 7. Chronic neuromuscular or neurodegenerative diseases