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A Radiotracer ([18F]FluorThanatrace) by PET/CT for the Imaging of Breast Cancer
Sponsor: M.D. Anderson Cancer Center
Summary
This phase II trial tests whether \[18F\]FluorThanatrace by positron emission tomography (PET)/computed tomography (CT) can improve imaging techniques in patients with breast cancer undergoing a standard of care biopsy or surgery. \[18F\]FluorThanatrace is a new radioactive tracer, which is a type of imaging agent that is labeled with a radioactive tag and injected into the body to help with imaging scans. PET is an established imaging technique that utilizes small amounts of radioactivity attached to very minimal amounts of tracer, in the case of this research, \[18F\]FluorThanatrace. Because some cancers take up \[18F\]FluorThanatrace it can be seen with PET. CT utilizes x-rays that traverse body from the outside. CT images provide an exact outline of organs and potential inflammatory tissue where it occurs in patient's body. \[18F\]FluorThanatrace by PET/CT may help detect the activity of a certain enzyme in the body that may be related to cancer growth in patients with breast cancer.
Official title: Imaging Using the Novel Radiotracer [18F] FluorThanaTrace([18F]FTT) by PET/CT in Patients With Breast Cancer
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
36
Start Date
2023-02-27
Completion Date
2026-08-20
Last Updated
2025-12-15
Healthy Volunteers
Yes
Conditions
Interventions
Computed Tomography
Undergo \[18F\]FFT PET/CT
Fluorine F 18 Fluorthanatrace
Given IV
Positron Emission Tomography
Undergo \[18F\]FFT PET/CT
Locations (3)
Siteman Cancer Center at Washington University
St Louis, Missouri, United States
University of Pennsylvania/Abramson Cancer Center
Philadelphia, Pennsylvania, United States
M D Anderson Cancer Center
Houston, Texas, United States