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RECRUITING
NCT05229341
NA

Evaluation of DNA Methylation Signatures for the Diagnosis and Management of Thyroid Nodules

Sponsor: City of Hope Medical Center

View on ClinicalTrials.gov

Summary

This clinical trial evaluates deoxyribonucleic acid (DNA) methylation signatures in diagnosing and managing thyroid nodules. The purpose of this research is to develop a new test for thyroid cancer. This test will use needle biopsies (small collections of tissue with a needle) from the thyroid to determine whether the participant has a malignant (cancer) or benign (not showing cancer) thyroid tumor. The information learned from this trial may help develop a more accurate test so that patients do not have unnecessary surgeries for nodules that are thought to be suspicious but are actually benign.

Official title: Evaluation of DNA Methylation Signatures in Diagnosis and Management of Thyroid Nodules

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

1450

Start Date

2021-10-22

Completion Date

2026-10-22

Last Updated

2026-02-23

Healthy Volunteers

No

Interventions

PROCEDURE

Diagnostic Procedure

Analysis via DDMS-2

OTHER

Electronic Health Record Review

Review of medical records

PROCEDURE

Needle Biopsy

Undergo needle biopsy

Locations (1)

City of Hope Medical Center

Duarte, California, United States