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RECRUITING
NCT05232331
NA

Intake of Nitrate-rich Vegetables and Their Effect on Inflammatory Molecules and Oral Microbiota of Patients With Periodontitis

Sponsor: University of Guadalajara

View on ClinicalTrials.gov

Summary

Vegetables, mainly green leafy ones and some others like beets, are a rich source of nitrate. Nitrate metabolism has shown benefits to the body and there are recent studies that agree that the consumption of nitrates from vegetables can modify the oral microbiota by increasing species with nitrate-reducing capacity, which are also bacteria that are associated with oral health.

Official title: Effect of Nitrate-rich Vegetable Intake on Inflammatory Molecule Levels, Nitrate-reducing Capacity and Oral Microbiota Composition in Patients With Periodontitis

Key Details

Gender

All

Age Range

30 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

60

Start Date

2021-06-23

Completion Date

2025-12-31

Last Updated

2024-08-16

Healthy Volunteers

No

Interventions

DIETARY_SUPPLEMENT

Intake of nitrate rich vegetables

Nutritional intervention for 10 weeks to increase the consumption of vegetables rich in nitrate. At the beginning of the NSPT on visit 1 (week 2), the first of 5 nutritional interventions will begin with the objective of consuming \~ 350 mg of nitrate daily from vegetables

Locations (1)

Integral Dental Clinics CUCS UDG

Guadalajara, Jalisco, Mexico