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Monoclonal Antibody Duration of REsponse in MIgraine After Treatment Interruption
Sponsor: Hospital Clínico Universitario de Valladolid
Summary
Observational analytic study with a prospective cohort design. Patients with episodic and chronic migraine that have responded to monoclonal antibodies (mAbs) versus calcitonin gene-related peptide (CGRP) or its receptor with positive response will be included. A headache diary will be completed in a daily basis. The primary outcome will be the time elapsed between the discontinuation of the monoclonal antibody and the return to the clinical situation at the moment of the mAbs onset. The potential variables that may be associated with a more sustained benefit will be explored.
Official title: Monoclonal Antibody Duration of REsponse in MIgraine After Treatment Interruption: A Prospective National Study
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
OBSERVATIONAL
Enrollment
200
Start Date
2022-02-15
Completion Date
2024-08-15
Last Updated
2024-04-29
Healthy Volunteers
No
Conditions
Interventions
Headache calendar completion
The patient will complete an in-paper or electronic calendar, depicting the presence/absence of headache, the median intensity and the need of acute medication.
Locations (1)
Hospital Clínico Universitario de Valladolid
Valladolid, Spain