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FTT PET/CT in Metastatic Prostate Cancer
Sponsor: Abramson Cancer Center at Penn Medicine
Summary
Up to 30 men with metastatic prostate cancer will undergo up to 2 FTT PET/CT scans to look at PARP activity in sites of known cancer. Subjects will undergo a baseline scan prior to starting new therapy and a second, optional, post-therapy scan 1-21 days after the start of treatment. Tissue from a clinical or research biopsy will be compared to imaging measures, if available.
Official title: Evaluating in Vivo PARP-1 Expression With 18F-FluorThanatrace Positron Emission Tomography (PET/CT) in Patients With Metastatic Prostate Cancer
Key Details
Gender
MALE
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
30
Start Date
2023-03-01
Completion Date
2026-07
Last Updated
2025-07-11
Healthy Volunteers
Not specified
Conditions
Interventions
[18F]FluorThanatrace
Investigational radiopharmaceutical used with Positron Emission Tomography (PET/CT) imaging that may provide a non-invasive measurement of PARP-1 expression
Locations (1)
University of Pennsylvania Hospital
Philadelphia, Pennsylvania, United States