Clinical Research Directory

Inclusion Criteria SCI Participants. Patients who suffer a traumatic spinal cord injury who meet the following inclusion criteria are eligible for admission into the study as "SCI participants": * Male or Female ≥ 19 years of age * Blunt (non-penetrating) traumatic spinal cord injury * Baseline neurologic impairment deemed "complete"(AIS A) or "incomplete" (AIS B, C, D) * Bony spinal level involvement between C0 and L1 inclusive * Ability to have initial blood sample drawn within 24 hours of injury * Have either an arterial line, central line, or intravenous line for collecting blood samples * Able and willing to provide informed consent Non-SCI Spine Trauma Control Participants. Patients who suffer a fracture or dislocation of their spinal column without neurologic injury who meet the following inclusion criteria are eligible for admission into the study as "Non-SCI Spine Trauma Control Participants": * Male or Female ≥ 19 years of age * Traumatic spinal fracture between C0 and L1 without spinal cord injury * Collection of initial blood sample within 24 hours of injury * Have either an arterial line, central line, or intravenous line for collecting blood samples * Able and willing to provide informed consent Exclusion Criteria Patients who fulfill any of the following criteria are not eligible for admission into the study: * Penetrating spinal cord injury (e.g. gunshot, stab) * Spinal cord injury with sensory deficit only (i.e. no motor deficit) * Spinal injury below L1 * Isolated radiculopathy without fracture * Isolated cauda equina injury * Pre-existing thromboembolic disease or coagulopathy (disorders related to blood clotting), such as haemophilia or von Willebrand's disease * Have any other medical condition that in the investigator's opinion would render the study procedures dangerous or impair their ability to receive treatment