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Susceptibility-Guided Therapy for Helicobacter Pylori Infection Treatment
Sponsor: Shanghai Zhongshan Hospital
Summary
This multicenter randomized controlled clinical trial was conducted to compare the eradication efficacy and health economic benefits of individualized regimens based on HP drug resistance mutation gene detection (multiple PCR method), individualized regimens based on HP traditional drug sensitivity testing (E-test method) and empirical regimens in the Helicobacter pylori treatment.
Official title: Clinical Efficacy and Health Economic Evaluation of Susceptibility-Guided Therapy for Helicobacter Pylori Infection Treatment：Multicenter Randomized Controlled Study
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
0
Start Date
2022-03-25
Completion Date
2023-03-01
Last Updated
2026-08-04
Healthy Volunteers
No
Conditions
Interventions
Esomeprazole
20mg bid
Bismuth potassium citrate
0.6g bid
Metronidazole
0.4g qid
Clarithromycin
0.5g bid
Levofloxacin
0.5g qd
Amoxicillin
1g bid
Tetracycline
0.5g qid
Locations (3)
Renji Hospital, School of Medicine, Shanghai Jiaotong University
Shanghai, Shanghai Municipality, China
Zhongshan Hospital, Fudan University
Shanghai, Shanghai Municipality, China
Huashan Hospital, Fudan University
Shanghai, Shanghai Municipality, China