Clinical Research Directory
Browse clinical research sites, groups, and studies.
Prognostic Impact of Lesion-specific Hemodynamic Index in Patients With Coronary Artery Disease
Sponsor: Seoul National University Hospital
Summary
The investigators aim to investigate the additive prognostic value of lesion-specific hemodynamic index such as ΔFFR, non-hyperemic pressure ratio such as RFR, over % diameter stenosis and FFR according to treatment strategy, and to find the prognostic implications of post-PCI FFR after adjustment of various clinical and disease characteristics, and to construct a comprehensive risk prediction model for post-PCI outcomes.
Official title: Prognostic Impact of Lesion-specific Hemodynamic Index and Disease Characteristics in Patients With Coronary Artery Disease Assessed by Fractional Flow Reserve
Key Details
Gender
All
Age Range
20 Years - Any
Study Type
OBSERVATIONAL
Enrollment
2429
Start Date
2021-08-01
Completion Date
2026-12-31
Last Updated
2022-02-22
Healthy Volunteers
No
Conditions
Interventions
Fractional flow reserve
Physiologic assessment includes Δ FFR (lesion-specific) and FFR (vessel-specific) measurement. Δ FFR is defined as a pressure step up across the lesion. Coronary angiography and physiologic assessment will be analyzed by an independent core laboratory (Seoul National University Hospital, Clinical Trial Center, Seoul, South Korea).
Locations (1)
Seoul National University Hospital
Seoul, South Korea