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Lesion-to-lesion Comparison of 68Ga-HA-DOTATATE, 18F-DOPA, and 18F-FDG PET/CT in the Evaluation of Metastatic Neuroendocrine Tumors
Sponsor: University of Alberta
Summary
This study is a single centre non-randomized non-blinded phase II prospective cohort study including 50 participants. The objective of this study is to directly compare 68Ga-HA-DOTATATE, 18F-DOPA, and 18F-FDG activity in patients with metastatic neuroendocrine tumors (NETs) on a lesion-by-lesion basis. The investigators will determine the prevalence of concordant versus discordant disease. Secondary objectives include assessing the standardized uptake value (SUV) and determining if there is any correlation between discordance and disease progression.
Key Details
Gender
All
Age Range
40 Years - Any
Study Type
INTERVENTIONAL
Enrollment
50
Start Date
2022-10-15
Completion Date
2026-06-30
Last Updated
2025-11-17
Healthy Volunteers
No
Conditions
Interventions
18F-DOPA with furosemide
Diagnostic 18F-DOPA PET/CT scan
Locations (1)
University of Alberta Hospital
Edmonton, Alberta, Canada