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ACTIVE NOT RECRUITING
NCT05255159
PHASE2

Lesion-to-lesion Comparison of 68Ga-HA-DOTATATE, 18F-DOPA, and 18F-FDG PET/CT in the Evaluation of Metastatic Neuroendocrine Tumors

Sponsor: University of Alberta

View on ClinicalTrials.gov

Summary

This study is a single centre non-randomized non-blinded phase II prospective cohort study including 50 participants. The objective of this study is to directly compare 68Ga-HA-DOTATATE, 18F-DOPA, and 18F-FDG activity in patients with metastatic neuroendocrine tumors (NETs) on a lesion-by-lesion basis. The investigators will determine the prevalence of concordant versus discordant disease. Secondary objectives include assessing the standardized uptake value (SUV) and determining if there is any correlation between discordance and disease progression.

Key Details

Gender

All

Age Range

40 Years - Any

Study Type

INTERVENTIONAL

Enrollment

50

Start Date

2022-10-15

Completion Date

2026-06-30

Last Updated

2025-11-17

Healthy Volunteers

No

Interventions

DIAGNOSTIC_TEST

18F-DOPA with furosemide

Diagnostic 18F-DOPA PET/CT scan

Locations (1)

University of Alberta Hospital

Edmonton, Alberta, Canada