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Efficacy/Safety of Midurethral Sling
Sponsor: Mackay Medical College
Summary
The trans-obturator tape (TOT), which exhibits a satisfactory cure rate and a relatively diminished invasiveness, has been increasingly accepted as a surgical treatment of stress urinary incontinence (SUI) patients. Nevertheless, in contrast to the well-recognized therapeutic benefit of the enhanced resistance to the bladder continence during urine storage, if the voiding function of the bladder adapts to the TOT-enhanced outlet resistance has not been adequately investigated. This study retrospectively assayed the voiding efficacy of each voiding cycle, to clarify if the thermodynamic efficacy of the bladder was modified in response to the TOT surgery.
Official title: Evaluation of Efficacy and Safety of Midurethral Slings in Women With Stress Incontinence
Key Details
Gender
FEMALE
Age Range
30 Years - 100 Years
Study Type
INTERVENTIONAL
Enrollment
200
Start Date
2021-03-08
Completion Date
2026-03
Last Updated
2025-09-05
Healthy Volunteers
No
Conditions
Interventions
Urodynamic investigations before and after a trans-obturator tape protocol.
Urodynamic investigations (The urodynamic study included free uroflowmetry, postvoid residual, filling and voiding cystometry, and a urethral pressure profile. The filling cystometry and urethral pressure profile were performed with 37 degrees C normal saline similar to body temperature at an infusion rate of 80 ml/min.)
Urodynamic investigations before and after a tension-free vaginal tape-obturator (TVT-O)
Urodynamic investigations (stated above.)
Urodynamic investigations before and after a mini Arc protocol.
Urodynamic investigations (stated above)
Urodynamic investigations before and after an i-STOP mini adjustable sling protocol.
Urodynamic investigations (stated above)
Urodynamic investigations before and after an Solyx sling protocol.
Urodynamic investigations (stated above.)
Locations (1)
Department of Obstetrics and Gynecology
New Taipei City, Taiwan