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Brain Activity During Bladder Filling: Pilot Study of an fMRI Protocol
Sponsor: University Hospital, Ghent
Summary
Urinary incontinence is the most frequently observed lower urinary tract symptom (LUTS) in children with cerebral palsy (CP) (Samijn et al., 2016). Higher brain centers responsible for bladder function may be related to the presence of incontinence. The current pilot study is the first study of a research project focusing on correlations between brain damage and incontinence.
Official title: Pilot Study: Apllicability of an fMRI Protocol for Incontinence Research
Key Details
Gender
All
Age Range
20 Years - 35 Years
Study Type
INTERVENTIONAL
Enrollment
6
Start Date
2025-05-01
Completion Date
2026-09-30
Last Updated
2024-06-05
Healthy Volunteers
Yes
Conditions
Interventions
invasive urodynamic evaluation
Invasive urodynamic evaluation to define maximum cystometric capacity. By means of catheterisation the bladder gets filled and volumes en pressures are measured.
functional magnetic resonance imaging during bladder filling
Functional MRI is used to capture brain activity during tasks. The task in the current study is bladder infusion and withdrawal by means of the INFSYS-2 infusion/withdrawal pump (Leitner et al. 2017)
Locations (1)
Ghent University Hospital
Ghent, Flanders, Belgium