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Evaluation of Four New Ready to Drink Oral Nutritional Supplements: Adult ONS Trial
Sponsor: Nutricia UK Ltd
Summary
The aim of this study is to evaluate compliance, acceptability, gastrointestinal tolerance, nutrient intake, appetite, nutritional status, and safety of four new ready to drink ONS. This is a prospective, longitudinal, 28-day intervention study with a 1-day baseline period. During the intervention period, patients will receive one of the four ONS for 28 days alongside their routine diet.
Official title: Evaluation of Four New Ready to Drink Oral Nutritional Supplements for the Management of Disease-related Malnutrition in Adults.
Key Details
Gender
All
Age Range
16 Years - Any
Study Type
INTERVENTIONAL
Enrollment
100
Start Date
2021-09-27
Completion Date
2026-12-31
Last Updated
2025-02-26
Healthy Volunteers
No
Conditions
Interventions
Dietary supplement (ONS)
At baseline, the investigating dietitian/nurse will record several measures, including clinical history and symptoms over the previous 24 hours. In addition, patients who are already receiving an ONS will continue their prescribed ONS for 1 day in which their gastrointestinal tolerance, ONS compliance and acceptability will be recorded. All patients will then receive standardised dietary advice in addition to one of the four trial ONS products daily for 28 days. The type of ONS will be agreed with the patient and the investigating dietitian/nurse, and the ONS prescription will be determined on an individual basis by the investigating dietitian/nurse responsible for the patient's nutritional management (1-3 ONS per day; aligned with guidelines set out within the Malnutrition Pathway). The type of ONS prescribed will be the same throughout the 28 days and will be taken orally.
Locations (19)
Ashford and St Peter's Hospitals NHS Foundation Trust
Ashford, United Kingdom
West Walk Surgery
Bristol, United Kingdom
Rowden Surgery
Chippenham, United Kingdom
Sirona Care & Health
Clevedon, United Kingdom
Mountainhall Treatment Centre
Dumfries, United Kingdom
Royal Surrey NHS Foundation Trust
Guildford, United Kingdom
Preston Hill Surgery
Harrow, United Kingdom
Honiton Surgery
Honiton, United Kingdom
James Alexander Family Practice
Hull, United Kingdom
NHS Highland
Inverness, United Kingdom
Airedale NHS Foundation Trust
Keighley, United Kingdom
Kings Cross Hospital
London, United Kingdom
Northumbria Healthcare NHS Foundation Trust
Newcastle, United Kingdom
Norfolk Community Health and Care NHS Trust
Norwich, United Kingdom
Nottingham University Hospitals NHS Trust
Nottingham, United Kingdom
Glan Clwyd Hospital
Rhyl, United Kingdom
Trowbridge Health Centre
Trowbridge, United Kingdom
Cowplain Family Practice
Waterlooville, United Kingdom
Yeovil District Hospital
Yeovil, United Kingdom