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Observational Study for Assessing Treatment and Outcome of Patients With Primary Brain Tumours Using cIMPACT-NOW and 2021 WHO Classification
Sponsor: European Organisation for Research and Treatment of Cancer - EORTC
Summary
Every new classification depends on its prognostic power and on the type of treatment given. With the rapid evolution of diagnostic methods and the advance in new treatments, there is much less reliable information available on how patients with newly defined brain tumour entities should be treated and what to expect from the current treatments. The goal is to determine whether the new 2021 WHO classification, based on cIMPACT-NOW recommendations, results in more homogeneous patient groups than the old 2016 classification. Furthermore, it will help derive provisional guidelines on how patients with these newly defined tumour entities are best treated. These recommendations will be based on the experience of EORTC investigators with chosen treatments and their experience as reported in this data collection report.
Official title: Observational Study for Assessing Treatment and Outcome of Patients With Primary Brain Tumours Diagnosed According to cIMPACT-NOW Recommendations and the 2021 WHO Classification
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
1650
Start Date
2023-03-21
Completion Date
2038-07-29
Last Updated
2025-12-17
Healthy Volunteers
No
Conditions
Interventions
Observational
The goal is to determine whether the new 2021 WHO classification, based on cIMPACT-NOW recommendations, results in more homogeneous patient groups than the old 2016 classification. Furthermore, it will help derive provisional guidelines on how patients with these newly defined tumour entities are best treated. These recommendations will be based on the experience of EORTC investigators with chosen treatments and their experience as reported in this data collection report.
Locations (42)
Innsbruck Universitaetsklinik
Innsbruck, Austria
Universitaetsklinikum Wien - AKH unikliniken
Vienna, Austria
Onze Lieve Vrouw Ziekenhuis
Aalst, Belgium
Institut Jules Bordet
Anderlecht, Belgium
Universitair Ziekenhuis Brussel
Brussels, Belgium
C.H.U. Sart-Tilman
Liège, Belgium
AZ Delta - Campus Rumbeke
Roeselare, Belgium
CHU Lyon - Hopital neurologique Pierre Wertheimer
Lyon, France
Hopital de La Timone
Marseille, France
Hopital la Pitie-Salpetriere
Paris, France
Knappschaft Krankenhaus Langendreer
Bochum, Germany
Universitaetsklinikum Bonn
Bonn, Germany
Universitaetsklinikum Koeln
Cologne, Germany
Universitaetsklinikum - Essen
Essen, Germany
University Hospital Frankfurt -Senckenberg Institute of Neurooncology
Frankfurt, Germany
Universitaetsklinikum Jena
Jena, Germany
Universitaetsklinikum Leipzig-Klinik fuer Strahlentherapie und Radioonkologie
Leipzig, Germany
Universitaetsklinikum Regensburg
Regensburg, Germany
Diagnostic & Therapeutic Center of Athens Hygeia Hospital S.A.
Athens, Greece
Ospedale Bellaria-Bologna
Bologna, Italy
Azienda Ospedaliero-Universitaria Careggi
Florence, Italy
Istituto Neurologico Carlo Besta
Milan, Italy
IRCCS Ospedale San Raffaele
Milan, Italy
Istituto Oncologico Veneto
Padova, Italy
IRCCS-Regina Elena National Cancer Center
Roma, Italy
Ospedale San Giovanni - Dipartimento Neuroscienze
Torino, Italy
The Netherlands Cancer Institute-Antoni Van Leeuwenhoekziekenhuis
Amsterdam, Netherlands
Leiden University Medical Centre
Leiden, Netherlands
Erasmus MC
Rotterdam, Netherlands
Oslo University Hospital - Radiumhospitalet
Oslo, Norway
Centro Hospitalar Universitario Lisboa Norte - Hospital Sta. Maria
Lisbon, Portugal
Instituto Portugues de Oncologia de Lisboa Francisco Gentil - EPE
Lisbon, Portugal
Institut Catala d'Oncologia - ICO L'Hospitalet - Hospital Duran i Reynals
L'Hospitalet de Llobregat, Barcelona, Spain
Hospital Clinic de Barcelona
Barcelona, Spain
Hospital De La Santa Creu I Sant Pau
Barcelona, Spain
Hospital Germans Trias i Pujol (Institut Catala D'Oncologia)
Barcelona, Spain
Hospital Duran i Reynals
L'Hospitalet de Llobregat, Spain
Centre Hospitalier Universitaire Vaudois
Lausanne, Switzerland
UniversitaetsSpital Zurich - Neurology Clinic
Zurich, Switzerland
NHS Lothian - The Royal Infirmary Of Edinburgh
Edinburgh, United Kingdom
Newcastle Hospitals NHS Trust - Freeman Hospital, Northern Centre For Cancer Care
Newcastle upon Tyne, United Kingdom
Nottingham University Hospitals NHS Trust - City Hospital
Nottingham, United Kingdom