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RECRUITING
NCT05272293
PHASE1/PHASE2

Immunotherapy With ex Vivo Expanded Haploidentical Natural Killer Cells for Children/Young Adults With AML

Sponsor: Belarusian Research Center for Pediatric Oncology, Hematology and Immunology

View on ClinicalTrials.gov

Summary

The purpose of this study is to estimate the efficacy of immunotherapy with ex vivo expanded haploidentical NK cells for children/young adults with primary high risk or refractory AML and relapsed AML.

Official title: Immunotherapy With ex Vivo Expanded Haploidentical Natural Killer Cells for Children/Young Adults With High-risk, Refractory or Relapsed AML

Key Details

Gender

All

Age Range

6 Months - 30 Years

Study Type

INTERVENTIONAL

Enrollment

15

Start Date

2021-11-01

Completion Date

2026-06

Last Updated

2024-08-28

Healthy Volunteers

No

Interventions

BIOLOGICAL

NK cell infusions

Three doses of expanded haploidentical NK cells (30-100 x 10\^6 cells /kg).

Locations (1)

Belarussian Research Center for Pediatric Oncology, Hematology and Immunology

Minsk, Minsk Oblast, Belarus