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ACTIVE NOT RECRUITING
NCT05275101
NA

Neural Mechanisms and Predictors of an Ultra-Brief Suicide Prevention Strategy

Sponsor: Ohio State University

View on ClinicalTrials.gov

Summary

The current study is a clinical trial, meaning a research study in which human subjects are prospectively assigned to one or more interventions to evaluate the effects of those interventions on health-related behavioral outcomes. Specifically, male and female adults with current suicidal intent will be randomly assigned to receive either a 1-hour session of crisis response planning (CRP) or a 1-hour session of standard crisis risk management (Treatment as Usual). The effects of both conditions on changes in emotion regulation, behavioral inhibition, stress reactivity, and suicide risk will be evaluated post-intervention and at six-month follow-up. Additional assessments of changes in mood and suicidality will be collected daily during the first 10-days following intervention, and then monthly for a duration of six months. A cohort of healthy controls is included in the study but are not randomized to either treatment condition. The investigators hypothesize the following: 1) A single session of CRP will acutely change suicide risk and 2) Individuals who receive CRP will show sustained improvements in measures of suicidality when compared to individuals who received the Treatment as Usual intervention.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

191

Start Date

2021-07-28

Completion Date

2026-04-01

Last Updated

2026-02-05

Healthy Volunteers

Yes

Conditions

Interventions

BEHAVIORAL

Crisis Response Planning

Individuals complete an experimental collaborative suicide intervention.

BEHAVIORAL

Crisis Risk Counseling

Individuals complete a standard crisis risk management intervention.

Locations (1)

Ohio State University

Columbus, Ohio, United States