Clinical Research Directory
Browse clinical research sites, groups, and studies.
Role of Photic and Non-photic Time Cues in Resetting Circadian Rhythms
Sponsor: Brigham and Women's Hospital
Summary
The aim of this study is to determine the principal time cue (light or meals) for resetting circadian rhythms in melatonin and metabolic outcomes.
Official title: Determining the Role of Photic and Non-photic Time Cues in Resetting Circadian Rhythms in Humans
Key Details
Gender
All
Age Range
18 Years - 30 Years
Study Type
INTERVENTIONAL
Enrollment
47
Start Date
2022-07-29
Completion Date
2026-07-31
Last Updated
2026-08-06
Healthy Volunteers
Yes
Conditions
Interventions
Bright Light
6.5-hour 10,000 lux light pulse (4100K fluorescent light) centered within the 16-hour wake episode (start 4.75 hour after wake and end 11.25 hour after wake).
Time-restricted eating
6.5-hour restricted meal window (4 meals at 4.75, 6.9, 9.1, 11.25 hours after waking) centered within the 16-hour wake episode.
Dim light
dim light (\<3 lux) throughout the 16-hour wake episode
12-h meal window
12-hour restricted meal window (4 meals at 2, 6, 10, and 14 hours after waking) centered within the 16-hour wake episode.
Locations (1)
Brigham and Women's Hospital
Boston, Massachusetts, United States