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The Electronic Medical Records and GEnomics (eMERGE) Network Genomic Risk Assessment
Sponsor: Vanderbilt University Medical Center
Summary
The eMERGE Network embraces the opportunity to use new methods in genomic medicine, information science, and research participant engagement to identify people at very high risk for specific diseases and recommend individualized approaches to prevention and care. The investigators will conduct a prospective study, with diverse and underserved participants, across ten eMERGE study sites to evaluate clinical implementation of a Genome Informed Risk Assessment (GIRA) tool that combines genetic, family history, and clinical risk information from participants.
Key Details
Gender
All
Age Range
3 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
26877
Start Date
2022-02-16
Completion Date
2026-12-31
Last Updated
2025-08-29
Healthy Volunteers
Yes
Conditions
Interventions
Genome Informed Risk Assessment (GIRA) report
A Genome Informed Risk Assessment (GIRA) report that combines genetic (monogenic risks and polygenic risk scores), family history, and clinical risk information from participants.
Locations (12)
University of Alabama Birmingham
Birmingham, Alabama, United States
Mountain Park Health Center
Tempe, Arizona, United States
Northwestern
Chicago, Illinois, United States
Massachusetts General Hospital
Boston, Massachusetts, United States
Brigham and Women's Hospital
Boston, Massachusetts, United States
Mayo Clinic
Rochester, Minnesota, United States
Mount Sinai
New York, New York, United States
Columbia University
New York, New York, United States
Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, United States
Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, United States
Vanderbilt University Medical Center
Nashville, Tennessee, United States
University of Washington
Seattle, Washington, United States