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Effect of Circadian Rhythm and Physical Exercise in Overweight Type 1 Diabetes Patients
Sponsor: Karolinska Institutet
Summary
Cardiometabolic risk in patients with abdominal obesity and type 1 diabetes can be moderated by life style modifications. There is an intimate link between gene regulation and circadian rhythm in mediating response to exercise in a variety of insulin sensitive organs. The aim of this project is to evaluate, by intervention, the interplay of circadian rhythm and high intensity interval training (HIIT) on glucose control and skeletal muscle metabolism in patients with overweight with or without type 1 diabetes (T1D).
Official title: Elucidating the Interplay Between Circadian Rhythm and Physical Exercise on Metabolism in Patients With Type 1 Diabetes and Overweight
Key Details
Gender
All
Age Range
18 Years - 50 Years
Study Type
INTERVENTIONAL
Enrollment
50
Start Date
2022-05-18
Completion Date
2026-10-31
Last Updated
2024-10-15
Healthy Volunteers
Yes
Conditions
Interventions
High intensity interval training (HIIT)
HIIT performed either in the morning or in the afternoon
Locations (1)
Ersta sjukhus
Stockholm, Sweden