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Intrapleural Nebulization of Bupivacain to Reduce Postoperative Pain
Sponsor: Assiut University
Summary
Thoracic surgery is now common and as other surgeries evolution of minimally invasive techniques is employed. Video-assisted thoracic surgery (VATS) produces little scar but may produce severe pain that may affect the pulmonary function. Many procedure was developed like intercostal nerve block which require injections at multiple levels, Insertion of local anaesthetic (LA) in the surgical drain but that was dangerous due to the large amount of LA and not sufficient to completely eliminate pain. Bupvicaine nebulization, through surgical port which won't make any other wound, thought to be sufficient because Nebulization will enable us better distribution and less amounts of LA. Bupvicaine is local anaesthetic amide group that works by blocking sodium channels thus preventing progression of action potential.
Official title: Pain Managment After VATS to Reduce Postoperative Pain and Improve Pulmonary Function
Key Details
Gender
All
Age Range
18 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2024-05-17
Completion Date
2024-07-15
Last Updated
2024-05-20
Healthy Volunteers
No
Conditions
Interventions
Intrapleural bupivacine nebulization
Intrapleural nebulization of bupivacine (10 ml of bupivacaine 0.5%) + Intravenous normal saline as a placebo
Intravenous paracetamol and ketorolac
Intravenous analgesia: paracetamol (one gram) and Ketorolac (30 mg) + Intrapleural normal saline (10 ml) as a placebo
Locations (1)
Assiut University
Asyut, Assuit, Egypt