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Sickle Cell Disease (SCD) Bone Pain Study
Sponsor: University of California, Davis
Summary
A prospective study to determine how low bone mineral density and/or vertebral compression fractures associate with pain in adults with sickle cell disease
Official title: Association Between Low Bone Density, Vertebral Fractures, and Pain in Sickle Cell Disease
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
53
Start Date
2022-11-03
Completion Date
2026-07-31
Last Updated
2025-08-24
Healthy Volunteers
No
Conditions
Interventions
Dual-energy X-ray absorptiometry
Measure bone mineral density at the lumbar spine, left total hip, left forearm, and whole body
Vertebral fracture analysis
Obtain thoracolumbar morphometry in DXA scan, then determine presence and severity of vertebral compression fractures by VFA
Adult Sickle Cell Quality of Life Measurement System pain impact questionnaire
Calculate patient-reported total pain scores to determine the pain phenotype of each study participant
Locations (1)
UC Davis Comprehensive Cancer Center
Sacramento, California, United States