Clinical Research Directory

Inclusion Criteria: * Individuals who are diagnosed with Primary Ciliary Dyskinesia OR * Individuals with abnormal PCD diagnostics (abnormal ciliary biopsy or PCD genetics) OR * Individuals with unexplained bronchiectasis OR * Individuals undergoing PCD diagnostic testing (ciliary biopsy, PCD genetic testing) or concern based on clinical symptoms (at least two of the following): * Neonatal respiratory distress * Organ laterality defects * Year-round cough starting in first year of life or bronchiectasis on chest CT * Year-round nasal congestion starting in first year of life or pansinusitis * Multiple ear infections in the first two years of life with sequelae (e.g. ear tubes, chronic effusion, abnormal audiological exam) * History of recurrent pneumonias (at least 2 in one year or more than 3 at any time) * Ability to provide consent for participation in study by the participants or guardian * Ability to perform the test * Age \>= 2 years of age Exclusion Criteria: * Individuals who are unable to understand the requirements of the study. * Individuals (or guardians) who are unwilling to provide consent. * Individuals who are unable to complete the testing * Recent history of sinus surgery (within four weeks) or bloody nose (within one week) of testing (they can be included at a later date) * Patients who are currently being treated (within one week) with antibiotics for sinusitis or respiratory symptoms (they can be included at a later date) * Age \<2 years of age