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RECRUITING
NCT05287464

International Multicentric Study ARON-1

Sponsor: Hospital of Macerata

View on ClinicalTrials.gov

Summary

The ARON-1 Study is designed as an International Multicentric Retrospective Study to collect global experiences with the use of immuno-combinations in patients with metastatic RCC. Two Supplementary Studies (ARON-1α and ARON-1β) have been designed. The ARON-1α Supplementary Study has been designed to investigate for the presence of genomic signatures from tumor samples of patients treated with first-line immuno-combinations for advanced RCC. The ARON-1β Supplementary Study has been designed to charaterize the immune cell populations and assess their relationship with the clinical outcome of mRCC patients treated with first-line immuno-combinations

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

1220

Start Date

2022-03-10

Completion Date

2027-09-30

Last Updated

2025-11-26

Healthy Volunteers

No

Interventions

DRUG

pembrolizumab plus axitinib

collect global experiences with the use of immuno-combinations in patients with metastatic RCC

Locations (1)

Ospedale di Macerata, UOC Oncologia

Macerata, Macerata, Italy