Clinical Research Directory

Eligibility Criteria for Substudies 1, 2, 4, 5 Inclusion Criteria: * Age 18 years or older Exclusion Criteria: * Patients with contraindication to MRI (e.g. pacemaker, contraindicated metallic implants, claustrophobia, etc) * Pregnant or trying to become pregnant (as determined by self-report during MRI safety screening) Eligibility Criteria for Substudy 3 Inclusion Criteria: * Age 7 years or older * One of: * Known or suspected liver iron overload * Known or suspected elevated liver fat Exclusion Criteria: * Patients with contraindication to MRI (e.g. pacemaker, contraindicated metallic implants, claustrophobia, etc) * Patients requiring intravenous (IV) conscious sedation for imaging are not eligible; patients requiring mild, oral anxiolytics for the MRI will be allowed to participate as long as the following criteria are met: * The subject has their own prescription for the medication. * The informed consent process is conducted prior to the self-administration of this medication * They come to the research visit with a driver * Pregnant or trying to become pregnant (as determined by self-report during MRI safety screening) Eligibility Criteria for Substudy 6 Inclusion Criteria: * Age 7 years or older * Scheduled for a clinical abdominal MRI exam Exclusion Criteria: * Patients with contraindication to MRI (e.g. pacemaker, contraindicated metallic implants, claustrophobia, etc) * Sedation required for MRI * Pregnant or trying to become pregnant (as determined by self-report during MRI safety screening)