Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

Back to Studies
RECRUITING
NCT05300685
PHASE3

Peri-operative Oral Pain Control Following Buccal Graft Urethroplasty

Sponsor: University of California, San Francisco

View on ClinicalTrials.gov

Summary

Patients undergoing buccal urethroplasty will often have significant post-operative oral pain from the graft site. Various graft harvest techniques and methods for post-harvest hemostasis including graft site closure have been explored. Despite the frequency of this clinical scenario there is no established best practice for peri-operative pain management in this patient population. In addition to traditional post operative pain control, groups have sought various peri-operative anesthetic regimens to improve post operative pain. This has led recently to the description of various regional blocks including buccal and periorbital blocks for peri-operative local anesthetic. No study has looked at superiority of regional pain management in this patient population. This study will aim to assess three established anesthetic protocols for oral pain control in a blinded, randomized controlled trial. Hypothesis: Patients who have buccal block will have lower post op pain without any increase adverse oral outcomes.

Official title: Peri-operative Oral Pain Control Following Buccal Graft Urethroplasty: Randomized Control Trial of Harvest Site Anesthetic

Key Details

Gender

MALE

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

60

Start Date

2022-02-15

Completion Date

2026-03-01

Last Updated

2025-10-24

Healthy Volunteers

No

Interventions

DRUG

Standard Buccal Harvest

Our institutions current anesthetic regimen. Comparison group

DRUG

Basic buccal procedure + Long acting local

Addition of long-acting local anesthetic to the wound bed following the oral graft harvest.

DRUG

Basic buccal procedure + Buccal block

Addition of long-acting local anesthetic as a buccal block after oral graft harvest

Locations (2)

University of California San Francisco

San Francisco, California, United States

MedStar Urology

Washington D.C., District of Columbia, United States