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Cytokine Expression in Psoriasis Patients with and Without Joint Involvement
Sponsor: Poitiers University Hospital
Summary
The objective of the resarch is to study the cytokine profile of patients with psoriatic arthritis and psoriasis in order to better understand the pathophysiology of the disease and the contribution of cytokines to the presence or absence of joint involvement. This research will compare cytokines levels in sera, in PBMC culture after LPS or CD3/CD28 agonist antibodies, and in skin biopsy.
Official title: Cytokine Expression in Sera, Ex Vivo Stimulated Peripheral Blood Mononuclear Cells Culture, and Skin in Psoriasis - Comparison of Patients with and Without Joint Involvement
Key Details
Gender
All
Age Range
18 Years - 100 Years
Study Type
INTERVENTIONAL
Enrollment
40
Start Date
2022-08-17
Completion Date
2026-08-18
Last Updated
2024-09-04
Healthy Volunteers
Yes
Conditions
Interventions
Blood sample collection
Blood sample collection
Skin sample collection
Skin sample collection
Locations (1)
Chu Poitiers
Poitiers, France