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WITHDRAWN
NCT05309902
PHASE1

A Study of Soticlestat in Healthy Adults To Evaluate the Effect on QTc Interval

Sponsor: Takeda

View on ClinicalTrials.gov

Summary

The main aim is to see if soticlestat has any effect in the heart rate. Participants will receive 4 doses of soticlestat in tablets and will complete some assessment which include to record activity of the heart and collection of blood samples. Then, the clinic will contact the participants 14 days after their final dose of soticlestat to check if they have any health problems.

Official title: A Phase 1, Double-Blinded, Placebo- and Active-Controlled, Randomized Study to Investigate the Potential of Soticlestat to Prolong the QTc Interval in Healthy Adult Participants

Key Details

Gender

All

Age Range

18 Years - 55 Years

Study Type

INTERVENTIONAL

Enrollment

0

Start Date

2022-10-11

Completion Date

2022-12-06

Last Updated

2026-08-19

Healthy Volunteers

Yes

Interventions

DRUG

Soticlestat

Soticlestat tablet.

DRUG

Placebo

Soticlestat placebo-matching tablet.

DRUG

Moxifloxacin

Moxifloxacin over-encapsulated tablet.

DRUG

Placebo

Moxifloxacin placebo-matching capsule.