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COMPLETED
NCT05311891

Variants of SARS-CoV-2 Causing COVID-19 in Africa

Sponsor: ANRS, Emerging Infectious Diseases

View on ClinicalTrials.gov

Summary

The main objective of this research is to identify and characterize the different molecular variants of SARS-CoV-2, emerging and / or circulating in several countries of Sub-Saharan Africa (Burkina Faso, Côte d'Ivoire, Gabon, Mali, Chad and Republic of Congo) and determine their role in the evolution of the pandemic.

Official title: Variants of SARS-CoV-2 in Central and West Africa: Frequency of Circulating Viruses and Implications for the Management and Control of the Pandemic

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

12600

Start Date

2022-09-30

Completion Date

2023-12-30

Last Updated

2026-10-16

Healthy Volunteers

Yes

Conditions

Interventions

DIAGNOSTIC_TEST

RT PCR

Characterize the different molecular variants of SARS-CoV-2, determine the escape potential of the new variants from neutralization by monoclonal antibodies and currently available vaccines and characterization of the mRNAs expressed in infected persons

Locations (6)

Centre de Référence pour les pathogènes émergents et réémergent

Bobo-Dioulasso, Burkina Faso

Centre Hospitalier Universitaire la Référence Nationale (CHU-RN)

N'Djamena, Chad

CIRBA

Abidjan, Côte d’Ivoire

Unité Mixte de Recherche CIRMF-SSM

Libreville, Gabon

SEREFO

Bamako, Mali

Laboratoire National de Santé Publique Brazzaville

Brazzaville, Republic of the Congo