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Aortic Compression Trial to Reduce Blood Loss at Cesarean Section
Sponsor: Karolinska Institutet
Summary
The goal of this clinical trial is to test if manual external aortic compression can prevent heavy blood loss in cesarean section. The main question\[s\] it aims to answer are: 1. Is external aortic compression effective? 2. Is external aortic compression safe? Participants will receive preventive manual external aortic compression or no external aortic compression (standard care) immediately after the baby is out at cesarean section. Blood loss will be measured, as well as kidney function, hemoglobin, and hematocrit before and after the operation. Experienced discomfort will be assessed the day after surgery and breastfeeding and signs of depression will be assessed using questionnaires after 2 months. Researchers will compare women with and without manual external aortic compression to see if there are differences in these outcomes.
Official title: Aortic Compression Trial - a Randomized Controlled Trial to Reduce Blood Loss at Cesarean Section (ACT)
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
2246
Start Date
2022-12-01
Completion Date
2028-12
Last Updated
2025-06-05
Healthy Volunteers
No
Interventions
External aortic compression
External aortic compression by assistant in cesarean section.
Locations (1)
Danderyd Hospital
Stockholm, Sweden