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ENROLLING BY INVITATION
NCT05312658
NA

Aortic Compression Trial to Reduce Blood Loss at Cesarean Section

Sponsor: Karolinska Institutet

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to test if manual external aortic compression can prevent heavy blood loss in cesarean section. The main question\[s\] it aims to answer are: 1. Is external aortic compression effective? 2. Is external aortic compression safe? Participants will receive preventive manual external aortic compression or no external aortic compression (standard care) immediately after the baby is out at cesarean section. Blood loss will be measured, as well as kidney function, hemoglobin, and hematocrit before and after the operation. Experienced discomfort will be assessed the day after surgery and breastfeeding and signs of depression will be assessed using questionnaires after 2 months. Researchers will compare women with and without manual external aortic compression to see if there are differences in these outcomes.

Official title: Aortic Compression Trial - a Randomized Controlled Trial to Reduce Blood Loss at Cesarean Section (ACT)

Key Details

Gender

FEMALE

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

2246

Start Date

2022-12-01

Completion Date

2028-12

Last Updated

2025-06-05

Healthy Volunteers

No

Interventions

PROCEDURE

External aortic compression

External aortic compression by assistant in cesarean section.

Locations (1)

Danderyd Hospital

Stockholm, Sweden