Clinical Research Directory

Inclusion Criteria:(Key) * Both genders; * Age ≥ 18 years old; * Full skeletal maturity; * Life expectancy over 5 years; * Patient is requiring primary unilateral arthroplasty based on physical examination and medical history; * Good bone quality evaluated by the Investigator and the intraoperative evaluation; * A diagnosis in the target shoulder of one or more of the S-11 SMR TT Hybrid Glenoid and Cementless Finned Short Stem Version Sep 2021 2.0 Confidential Page11 following: 1. Primary osteoarthritis; 2. Secondary osteoarthritis; 3. Post-traumatic arthritis; 4. Rheumatoid arthritis; 5. Avascular necrosis 6. acute fractures of the humeral head that cannot be treated with other fracture fixation methods; 7. cuff tear arthropathy (only in combination with CTA Heads); 8. Glenoid arthrosis without excessive glenoid bone loss: A1, A2 and B1 according to Walch classification. Exclusion Criteria (Key): * Patient requiring revision shoulder arthroplasty; * Osteoporosis with a history of non-traumatic fractures; * Steroid injections within the previous 3 months; * Contralateral shoulder replacement within the previous 3 months; * Significant proven or suspicious infection of the target shoulder or any serious infectious disease before the study according to the Investigator; * Significant neurological or musculoskeletal disorders that may compromise functional recovery; * Not recovered axillary nerve palsy; * Non functioning deltoid muscle; * Known or suspicious hypersensitivity to the metal or other components and materials of the implant; * Participation in any experimental drug/device study within the 6 months prior to the preoperative visit; * Women of childbearing potential who are pregnant, nursing, or planning to become pregnant. These are key eligibility criteria, other eligibility criteria apply.