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ACTIVE NOT RECRUITING
NCT05317689
PHASE1

Comparing the Effects of Psilocin and Psilocybin in Healthy Adults

Sponsor: University of California, San Francisco

View on ClinicalTrials.gov

Summary

To compare the physiological and psychological effects of psilocin taken orally by pill or sublingually by dissolving a tablet under the tongue to those of psilocybin taken by pill in healthy adults.

Official title: Comparison of the Effects of PEX20 (Oral Psilocin), PEX30 (Sublingual Psilocin), and PEX10 (Oral Psilocybin) in Healthy Adults

Key Details

Gender

All

Age Range

25 Years - 50 Years

Study Type

INTERVENTIONAL

Enrollment

20

Start Date

2022-05-26

Completion Date

2025-07

Last Updated

2025-06-10

Healthy Volunteers

Yes

Conditions

Interventions

DRUG

Psilocin

17.5mg oral psilocin with psychological support and physiological monitoring

DRUG

Psilocybin

25mg oral psilocybin with psychological support and physiological monitoring

DRUG

Sublingual Psilocin

2.18mg - 4.36mg sublingual psilocin with psychological support and physiological monitoring

Locations (1)

University of California, San Francisco

San Francisco, California, United States