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Assessing Gut Microbiota Mediated Health Outcomes of Whole Wheat and Its Major Bioactive Components
Sponsor: Ohio State University
Summary
This study will investigate the gut microbiota-mediated effects of whole wheat consumption on human health in adults with pre-diabetes. Participants will complete two phases of intervention in random order in which they will consume either whole wheat bread (4 servings) or white bread a day for two weeks prior to collecting specimens (stool, urine, and plasma/serum).
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
65
Start Date
2022-01-27
Completion Date
2026-05-30
Last Updated
2025-11-20
Healthy Volunteers
No
Interventions
Whole Wheat Bread
Standardized whole wheat bread (128 g daily)
White Bread (control)
Standardized white bread (128 g daily)
Locations (1)
The Ohio State University
Columbus, Ohio, United States