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Tranexamic Acid in Traumatic Brain Injury
Sponsor: Assiut University
Summary
In this study, our aim is to investigate the role of tranexamic acid for modulating the inflammation in patients with traumatic brain injury (TBI).
Official title: The Impact of Early Use of Tranexamic Acid in Traumatic Brain Injury Upon the Inflammatory Response and Outcome
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2022-05-18
Completion Date
2027-10-15
Last Updated
2026-01-02
Healthy Volunteers
No
Conditions
Interventions
Saline
Giving saline (loading dose of 1gm of saline 0.9%, followed by a 1gm of maintenance saline dose over 8 hours for 48 h).
Tranexamic acid
Giving TXA (loading dose of 1gm of TXA, followed by a 1gm of maintenance dose over 8 hours for 48 h).
Locations (1)
Assiut university hospital
Asyut, Assuit, Egypt