Clinical Research Directory

Inclusion Criteria: 1. Age ≥18 years 2. Clinically stable, symptomatic patients who present to ED/observation unit with suspected CAD 3. CCTA shows at least one ≥40% lesion and no lesions \>90% in at least one major epicardial vessel 4. FFR-CT processed successfully (if applicable) 5. EKG with no acute ischemic changes 6. Willing to comply with all aspects of the protocol, including adherence to follow up visit 7. Agrees to be included in the study 8. Able to provide written informed consent Exclusion Criteria: 1. CCTA showing no ≥40% lesion in a major epicardial vessel 2. CCTA showing a lesion \>90% in a major epicardial vessel 3. CCTA showing other incidental, non-cardiac findings requiring admission, e.g., pneumonia, pulmonary embolism, or aortic dissection 4. Uninterpretable CCTA which is not of diagnostic quality 5. Coronary artery bypass graft surgery (CABG) or percutaneous coronary intervention (PCI) prior to CCTA acquisition 6. Left main lesion \>50% 7. Confirmed acute coronary syndrome (acute myocardial infarction or unstable angina) 8. Known complex congenital heart disease or any history of coronary artery disease 9. Patients with tachycardia or significant arrhythmia which cannot be adequately controlled with medications to allow CTA 10. Any active, serious, life-threatening disease with a life expectancy of less than 2 months 11. Inability to comply with follow-up requirements 12. Currently enrolled in another study utilizing FFR-CT or in an investigational trial that involves a non-approved cardiac drug or device 13. Persons under the protection of justice, guardianship, or curatorship