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Effect of Protein, Mobility Therapy and Electric Stimulation on Recovery in Older ICU Survivors
Sponsor: University of Maryland, Baltimore
Summary
Older ICU survivors with ICU acquired weakness (ICUAW) are malnourished, sarcopenic, and functionally debilitated as a consequence of the high burden of comorbidities common in the elderly. To address the sequalae of critical illnesses, the investigators will perform a trial incorporating an intervention that combines mobility-based physical rehabilitation (MRP), high protein supplementation (HPRO), and neuromuscular electric stimulation (NMES). The investigators will then assess both clinical and functional outcomes and determine the relationship of disability with systemic inflammation.
Official title: Effect of Protein, Mobility Therapy and Electric Stimulation on Recovery in Older Survivors of Critical Illness
Key Details
Gender
All
Age Range
60 Years - 99 Years
Study Type
INTERVENTIONAL
Enrollment
78
Start Date
2025-12-01
Completion Date
2027-05-30
Last Updated
2025-07-15
Healthy Volunteers
No
Interventions
MRP and High Protein Supplement (HPRO) and Neuromuscular Electric Stimulation (NMES)
Mobility-based physical rehabilitation sessions performed 5 times/week by a study PT to provide strength and cardiopulmonary endurance training. High whey protein shakes prescribed to a total intake of 1.6-1.8 g/kg/d in 2 divided doses based on caloric needs. 2 x 30-minute lower extremity electric stimulation sessions/day, 5 times/wk performed by study PT.
Locations (1)
U of Maryland, Baltimore, Professional Schools IRB
Baltimore, Maryland, United States