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Functional Outcomes From Diets in Multiple Sclerosis
Sponsor: University of Alabama at Birmingham
Summary
The purpose of this study is to test the effects of two dietary interventions, glycemic load and calorie restriction, on physical function, cognition, pain, fatigue, mood, and anxiety in adults with multiple sclerosis (MS). The investigators will also explore the how the diet interventions impact inflammation, immunity, and metabolic biomarkers.
Official title: The Impact of Diet Quality and Calorie Restriction on Physical Function and Patient Reported Outcomes in Multiple Sclerosis
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
100
Start Date
2023-03-20
Completion Date
2026-11-01
Last Updated
2026-04-03
Healthy Volunteers
No
Interventions
Glycemic load
Participants will be provided food to meet GL prescription for the duration of the trial.
Calorie restriction
Participants will be provided food to meet their prescribed daily calorie intake for the duration of the trial (weight stable in first 16 weeks, weight loss in second 16 weeks).
Behavioral support
All participants will receive behavioral supports in the form of email, text, information pages and weekly calls from the study staff to maximize adherence.
Locations (2)
University of Alabama at Birmingham
Birmingham, Alabama, United States
Washington University
St Louis, Missouri, United States