Clinical Research Directory

Inclusion Criteria: * Patients with resectable cervical esophageal squamous cell carcinoma (cT1b-T4aN0-3M0); * Cervical esophageal cancers spreads upwards to involve the hypopharynx and downwards to involve the thoracic esophagus can also be included; * Aged 18-75 years; * Without any contraindication of operation; * Hemoglobin \>=90 g/L; Leukocytes \>=4.0x10\^9/L; Absolute neutrophil count \>=1.5x10\^9/L; Platelet \>=100x10\^9/L;Total bilirubin \<=1.5 ULN; ALT \<=2.5 ULN; AST \<=2.5 ULN; Serum creatinine \<=1.5 ULN or creatinine clearance rate \>=50 mL/min (Cocheroft-Gault);INR \<=1.5 ULN; APTT \<=1.5 ULN; * Without other malignancies; * Expected R0 resection; * ECOG PS 0-1; * Volunteered to participate in the study, signed the informed consent form. Exclusion Criteria: * Without other malignancies; * With mental diseases; * With hemorrhagic disease; * Inoperable patients; * Pregnant or lactating women; * Has a history of allergy to paclitaxel or cisplatin