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NCT05328765

A Global Record of Patients With Anal Squamous Cell Carcinoma With and Without HIV Infection

Sponsor: Latin American Cooperative Oncology Group

View on ClinicalTrials.gov

Summary

Due to the scarcity of data on prognostic and predictive influence on CCA, epidemiological studies evaluating these factors need to be developed in patients with CCA. Therefore, the investigators want to evaluate the profile of patients in the real world and from various parts of the world, describing prognostic factors such as CD4 dosage, time of HIV infection, evaluation of viral load, diagnosis of AIDS, geographic region of diagnosis and treatment, clinical staging, medications concomitant with QRT (risk of drug interactions), comorbidities (possible impact on dose-intensity), use of HAART, time of use of HAART, radiotherapy modality (conventional 3D vs Modulated Beam Intensity \[IMRT\], response to Nigro vs CTII regimens, as well as comparing clinical outcomes with patients without HIV infection.

Official title: ACTION HIV (Anal Cancer TherapIes and Outcomes iNitiative for Patients Living With and Without HIV): A Global Record of Patients With Anal Squamous Cell Carcinoma With and Without HIV Infection

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

369

Start Date

2023-06-09

Completion Date

2025-02-07

Last Updated

2026-08-28

Healthy Volunteers

No

Locations (11)

Hospital de Gastroenterología Carlos Bonorino Udaondo

Buenos Aires, Buenos Aires, Argentina

INCA - Instituto Nacional de Câncer

Rio de Janeiro, Rio de Janeiro, Brazil

HUOL - Hospital Universitário Onofre Lopes da UFRN

Natal, Rio Grande do Norte, Brazil

Liga Norte Riograndense Contra o Câncer

Natal, Rio Grande do Norte, Brazil

CEPON - Centro de Pesquisas Oncológicas

Florianópolis, Santa Catarina, Brazil

Hospital de Amor de Barretos

Barretos, São Paulo, Brazil

A.C. Camargo Cancer Center

São Paulo, São Paulo, Brazil

INCan - Instituto Nacional de Cancerología

Mexico City, Mexico City, Mexico

INEN - Instituto Nacional de Enfermedades Neoplásicas

Lima, Peru, Peru

Oncosalud AUNA

Lima, Peru, Peru

Hospital de Clínicas de Montevideo Dr. Manuel Quintela

Montevideo, Uruguai, Uruguay