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A Global Record of Patients With Anal Squamous Cell Carcinoma With and Without HIV Infection
Sponsor: Latin American Cooperative Oncology Group
Summary
Due to the scarcity of data on prognostic and predictive influence on CCA, epidemiological studies evaluating these factors need to be developed in patients with CCA. Therefore, the investigators want to evaluate the profile of patients in the real world and from various parts of the world, describing prognostic factors such as CD4 dosage, time of HIV infection, evaluation of viral load, diagnosis of AIDS, geographic region of diagnosis and treatment, clinical staging, medications concomitant with QRT (risk of drug interactions), comorbidities (possible impact on dose-intensity), use of HAART, time of use of HAART, radiotherapy modality (conventional 3D vs Modulated Beam Intensity \[IMRT\], response to Nigro vs CTII regimens, as well as comparing clinical outcomes with patients without HIV infection.
Official title: ACTION HIV (Anal Cancer TherapIes and Outcomes iNitiative for Patients Living With and Without HIV): A Global Record of Patients With Anal Squamous Cell Carcinoma With and Without HIV Infection
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
369
Start Date
2023-06-09
Completion Date
2025-02-07
Last Updated
2026-08-28
Healthy Volunteers
No
Locations (11)
Hospital de Gastroenterología Carlos Bonorino Udaondo
Buenos Aires, Buenos Aires, Argentina
INCA - Instituto Nacional de Câncer
Rio de Janeiro, Rio de Janeiro, Brazil
HUOL - Hospital Universitário Onofre Lopes da UFRN
Natal, Rio Grande do Norte, Brazil
Liga Norte Riograndense Contra o Câncer
Natal, Rio Grande do Norte, Brazil
CEPON - Centro de Pesquisas Oncológicas
Florianópolis, Santa Catarina, Brazil
Hospital de Amor de Barretos
Barretos, São Paulo, Brazil
A.C. Camargo Cancer Center
São Paulo, São Paulo, Brazil
INCan - Instituto Nacional de Cancerología
Mexico City, Mexico City, Mexico
INEN - Instituto Nacional de Enfermedades Neoplásicas
Lima, Peru, Peru
Oncosalud AUNA
Lima, Peru, Peru
Hospital de Clínicas de Montevideo Dr. Manuel Quintela
Montevideo, Uruguai, Uruguay