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Impact of Propofol-Based Total Intravenous Anesthesia Versus Anesthesia With Sevoflurane on Long-term Outcomes With Patients Undergoing Elective Excision of Primary Liver Tumors
Sponsor: Kaohsiung Medical University Chung-Ho Memorial Hospital
Summary
This is a two-arm, parallel-group randomized clinical trial. Routine perioperative care would be performed in volunteers with primary Hepatocellular carcinoma. The study will enroll approximately 500 volunteers to compare the progression-free or overall survival in patients undergoing elective partial hepatectomy for primary liver tumors between propofol and sevoflurane for the maintenance of anesthesia.
Official title: Impact of Propofol-Based Total Intravenous Anesthesia Versus Anesthesia With Sevoflurane
Key Details
Gender
All
Age Range
20 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
500
Start Date
2022-04-26
Completion Date
2027-03-31
Last Updated
2022-11-30
Healthy Volunteers
No
Conditions
Interventions
Propofol
total intravenous anesthesia with propofol for the partial hepatectomy of hepatocellular carcinoma.
Sevoflurane
The sevoflurane group was maintained via sevoflurane vaporizer between 1% and 3% (target minimum alveolar concentration of 0.7-1.3 MAC).
Locations (1)
Kaohsiung Medical University Chung-Ho Memorial Hospital
Kaohsiung City, Taiwan