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Cumulus Cell Mitochondrial Activity as a Non-invasive Marker of Embryo Quality (FLIM)
Sponsor: Mỹ Đức Hospital
Summary
This study aims to test the extent of association of FLIM parameters of cumulus cells with clinical outcomes (clinical pregnancy, ongoing pregnancy at 12 weeks, and live birth) of the embryos that result from the enclosed oocytes.
Official title: Cumulus Cell Mitochondrial Activity as a Non-invasive Marker of Embryo Quality
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
200
Start Date
2022-04-25
Completion Date
2026-12-30
Last Updated
2026-03-18
Healthy Volunteers
No
Interventions
FLIM parameters
Cumulus samples (CCs) will be collected following the protocol on the day of oocyte pick up (OPU). CCs are frozen by the cryo-tech method, then stored in liquid nitrogen at -196oC. Information of CC samples and processed date/time is recorded. After all, samples are collected, they will be transferred to The Needleman Lab, Northwest Lab Building 359,52 Oxford Street Cambridge MA 02138 to measure mitochondria metabolism using FLIM.
Locations (1)
My Duc Hospital
Ho Chi Minh City, Ho Chi Minh City, Vietnam