Clinical Research Directory

Inclusion Criteria: * Patients documented clinical/pathologic 1) acute or chronic colon or skin GVHD, 2) Crohn's disease, or 3) colitis * Have acceptable hematologic status \[total hemoglobin (tHb) ≥ 7.0 mg/dL\] * Patients ≥ 18 yrs of age * Willing to comply with study procedures and be available for the duration of the study * Patient has ability to understand and the willingness to provide a signed and dated IRB-approved informed consent document. Exclusion Criteria: * Patients with a tattoo over the area of inflammation * Pregnant patients are not eligible for this trial. Eligible patients (if applicable) will be required to document the date of the first day of their last menstrual cycle, and provide a negative pregnancy test if sexually active and of childbearing potential * Patients who are breastfeeding * Any open wound (skin ulcerations or infections) at or near the site of imaging that would preclude MSOT imaging. * Any febrile illness that precludes or delays participation preoperatively