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China HeadAche DIsorders RegiStry
Sponsor: Beijing Tiantan Hospital
Summary
It is planned to include 10000 patients. In the China HeadAche DIsorders RegiStry CHAIRS）, patients aged over 12 years with primary headache and medication-overuse headache(MOH) were collected. The biomarkers, imaging features, cognition, genetic characteristics, ocial and demographic data, medical data, therapeutics used, and outcome of headache-related diseases were studied, and long-term follow-up was planned.
Key Details
Gender
All
Age Range
12 Years - Any
Study Type
OBSERVATIONAL
Enrollment
10000
Start Date
2022-08-29
Completion Date
2032-12-31
Last Updated
2026-07-10
Healthy Volunteers
No
Conditions
Interventions
Medicine Overuse Headache/New Daily Persistent Headache
At the end of the 24th month visit, the patient is free to choose whether to conduct a face-to-face visit once a year until death.
Episodic Migraine and Chronic Migraine
long-term follow-up
Patients with other types of primary headache
No collection Brain imaging、Cognitive function test、Biological sample
Yangxue Qingnao Granules (Pills)
Participants who, in routine clinical practice, were prescribed Yangxue Qingnao Granules/Pills for acute headache relief and/or preventive management were enrolled. Treatment initiation, dosing, frequency, and duration were determined by the treating physician and the patient and were not assigned by the study protocol. During the 12-week observation period, participants were followed and outcomes were recorded, including relief of up to four headache episodes (for those using the medication for acute treatment) and longitudinal symptom measures at weeks 4, 8, and 12 (for those receiving preventive management).
Erenumab
Participants who received eptinezumab for migraine prophylaxis in routine clinical practice were included. Treatment decisions (including whether to initiate eptinezumab, the selected dose \[e.g., 100 mg or 300 mg\], infusion interval, and duration) were made by the treating physician in consultation with the patient, and were not assigned by the study protocol. Patients were followed prospectively/retrospectively according to routine clinic visits, with outcome assessments captured at approximately 4-week intervals during the 12-week observation window (and additional follow-up when available).
Eptinezumab
Participants who received eptinezumab for migraine prophylaxis in routine clinical practice were included. Treatment decisions (including whether to initiate eptinezumab, the selected dose \[e.g., 100 mg or 300 mg\], infusion interval, and duration) were made by the treating physician in consultation with the patient, and were not assigned by the study protocol. Patients were followed prospectively/retrospectively according to routine clinic visits, with outcome assessments captured at approximately 4-week intervals during the 12-week observation window (and additional follow-up when available).
Locations (61)
Anqing Municipal Hospital
Anqing, Anhui, China
The First Affiliated Hospital of Wannan Medical College (Yijishan Hospital)
Wuhu, Anhui, China
Beijing Tiantan Hospital, Capital Medical University
Beijing, Beijing Municipality, China
Beijing Chaoyang Hospital
Beijing, Beijing Municipality, China
Peking University Third Hospital
Beijing, Beijing Municipality, China
The First Hospital of Fangshan District, Beijing
Beijing, Beijing Municipality, China
Chongqing People's Hospital
Chongqing, Chongqing Municipality, China
The Third Affiliated Hospital of Chongqing Medical University
Chongqing, Chongqing Municipality, China
Fujian Provincial Hospital
Fuzhou, Fujian, China
The First Affiliated Hospital of Xiamen University
Xiamen, Fujian, China
The Second Affiliated Hospital of Xiamen Medical College
Xiamen, Fujian, China
The Second Hospital of Lanzhou University
Lanzhou, Gansu, China
Shenzhen Second People's Hospital
Shenzhen, Guangdong, China
The First Affiliated Hospital of Guangxi University of Chinese Medicine
Nanning, Guangxi, China
The Second Affiliated Hospital of Guangxi Medical University
Nanning, Guangxi, China
The Second People's Hospital of Guiyang
Guiyang, Guizhou, China
The First People's Hospital of Zunyi
Zunyi, Guizhou, China
Ruijin-Hainan Hospital Shanghai Jiao Tong University School Of Medicine
Qionghai, Hainan, China
Qinhuangdao Haigang Hospital
Qinhuangdao, Hebei, China
Zhongnan Hospital of Wuhan University
Wuhan, Hebei, China
Qinghe County People's Hospital
Xingtai, Hebei, China
The First Affiliated Hospital of Hebei North University
Zhangjiakou, Hebei, China
Yangyuan County People's Hospital
Zhangjiakou, Hebei, China
Zhangjiakou First Hospital
Zhangjiakou, Hebei, China
The Second Affiliated Hospital of Harbin Medical University
Harbin, Heilongjiang, China
Luohe Central Hospital
Luohe, Henan, China
Luoyang Central Hospital
Luoyang, Henan, China
The Second Affiliated Hospital of Henan University of Science and Technology
Luoyang, Henan, China
Yiyang County People's Hospital
Luoyang, Henan, China
Xuchang Central Hospital
Xuchang, Henan, China
The 7th People's Hospital of Zhengzhou
Zhengzhou, Henan, China
The First Affiliated Hospital of Zhengzhou University
Zhengzhou, Henan, China
Zhengzhou Central Hospital
Zhengzhou, Henan, China
Baotou Central Hospital
Baotou, Inner Mongolia, China
Changzhou First People's Hospital
Changzhou, Jiangsu, China
Brain Hospital Affiliated to Nanjing Medical University
Nanjing, Jiangsu, China
Jiujiang First People's Hospital
Jiujiang, Jiangxi, China
The First Affiliated Hospital of Nanchang University
Nanchang, Jiangxi, China
The First Hospital of Jilin University
Changchun, Jilin, China
The Second Hospital of Jilin University
Changchun, Jilin, China
Ansteel Group General Hospital
Anshan, Liaoning, China
Huludao Central Hospital
Huludao, Liaoning, China
Shandong Provincial Hospital
Jinan, Shandong, China
Shandong Provincial Qianfoshan Hospital
Jinan, Shandong, China
Zibo Municipal Hospital
Zibo, Shandong, China
Shanghai Jiao Tong University School of Medicine Affiliated Tongren Hospital
Shanghai, Shanghai Municipality, China
The Second Hospital of Shanxi Medical University
Taiyuan, Shanxi, China
Chengdu Second People's Hospital
Chengdu, Sichuan, China
Hospital of Chengdu University of Traditional Chinese Medicine
Chengdu, Sichuan, China
Dachuan District People's Hospital
Dazhou, Sichuan, China
Deyang People's Hospital
Deyang, Sichuan, China
Guangyuan Hospital of Traditional Chinese Medicin
Guangyuan, Sichuan, China
The First People's Hospital of Guangyuan
Guangyuan, Sichuan, China
Nanchong Central Hospital
Nanchong, Sichuan, China
Panzhihua Central Hospital
Panzhihua, Sichuan, China
Siyang Hospital
Siyang, Sichuan, China
Zigong First People's Hospital
Zigong, Sichuan, China
Xinjiang Production and Construction Corps Hospital
Ürümqi, Xinjiang, China
The Second Affiliated Hospital of Zhejiang University School of Medicine
Hangzhou, Zhejiang, China
Huzhou Central Hospital
Huzhou, Zhejiang, China
The First Affiliated Hospital of Wenzhou Medical University
Wenzhou, Zhejiang, China