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Summary
This is a single-center study that aims to earn more about how two different compounds found in food, oxalate and citrate, may affect a person's chances of forming kidney stones.
Official title: Oxalate and Citrate in Humans
Key Details
Gender
All
Age Range
18 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
50
Start Date
2022-10-27
Completion Date
2026-12-01
Last Updated
2026-01-08
Healthy Volunteers
Yes
Conditions
Interventions
Kidney stones Normal controls Consuming a special drink (sodium oxalate) during an all day visit to the University of Chicago research clinic
Consuming a special drink (sodium oxalate) during an all day visit to the University of Chicago research clinic Subjects in both arms will be asked to partake in the same activities, as follows: The day before presenting to the research clinic subjects will collect urine at home. Subjects will will come in to the research clinic at the University of Chicago in Hyde Park, where they will spend most of the day. We will give them a special liquid that contains oxalate, and they will receive a specially prepared breakfast that is low in oxalate and citrate. After this, we will collect urine and blood throughout the day. While at the clinic, subjects will also receive specially prepared snacks.
Locations (1)
University of Chicago Medical Center
Chicago, Illinois, United States