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A Community Population Screening Cohort Study Based on Polygene Methylation Detection for Colorectal Cancer in Yangzhou
Sponsor: Singlera Genomics Inc.
Summary
This is a cross-sectional cohort study based on community population jointly developed by Northern Jiangsu People's Hospital and Shanghai Kunyuan Biological Technology Co., LTD. This study will verify the real world results of polygene methylation detection of colorectal cancer in a large prospective cohort of community population, which is expected to enroll 80,000 permanent residents in Yangzhou city. The preliminary design period of the study is 5 years. In this study, questionnaire survey and polygene methylation test of colorectal cancer were used as the primary screening method, and colonoscopy was used as the further validation examination method to screen colorectal cancer and precancerous lesions. The diagnosis and outcome of all lesions were based on colonoscopy and pathological examination. The evaluation indexes include sensitivity, specificity, detection rate of precancerous lesions and adenoma.
Key Details
Gender
All
Age Range
40 Years - 74 Years
Study Type
OBSERVATIONAL
Enrollment
80000
Start Date
2022-04-01
Completion Date
2027-04
Last Updated
2023-08-29
Healthy Volunteers
Yes
Conditions
Locations (2)
Northern Jiangsu People's Hospital
Yangzhou, Jiangsu, China
Yangzhou First People's Hospital
Yangzhou, Jiangsu, China